Thermo Fisher Scientific TWA1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GID8. Recombinant protein control fragment (Product #RP-99306). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TWA1,uniProtId:Q9NWU2-1,ncbiNodeId:9606,antigenRange:77-152,antigenLength:228,antigenImageFileName:PA5-62096_TWA1_Q9NWU2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62096_TWA1_Q9NWU2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641988

Product Specific Information

Immunogen sequence: GQIQEAIALI NSLHPELLDT NRYLYFHLQQ QHLIELIRQR ETEAALEFAQ TQLAEQGEES RECLTEMERT LALLAF

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.