Thermo Fisher Scientific TWA1 Polyclonal Antibody
Human GID8 단백질에 특이적인 Rabbit Polyclonal Antibody로 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS/glycerol buffer에 보존되며 연구용으로 적합.
- 카탈로그번호
- PA562096
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GID8 (Product #RP-99306) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term); -20°C (long term), avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2641988 |
Product Specific Information
Immunogen sequence:
GQIQEAIALI NSLHPELLDT NRYLYFHLQQ QHLIELIRQR ETEAALEFAQ TQLAEQGEES RECLTEMERT LALLAF
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
TWA1 was identified through a two-hybrid associated protein screen with RanBPM. TWA1 is well conserved through evolution and localized within the nucleus. It interacts with RanBP9 and forms a complex with RanBPM and Muskelin.
TWA1 possesses the LisH-CTLH motif, found in proteins involved in microtubule dynamics, cell migration, nucleokinesis, and chromosome segregation. These functions overlap with those of the RanGTPase cycle, suggesting additional roles within this pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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