Thermo Fisher Scientific BTBD7 Polyclonal Antibody
Human BTBD7 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC 및 ICC/IF 실험에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 버퍼에 40% 글리세롤 포함, 단기 4°C 보관 및 장기 -20°C 저장 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BTBD7. Recombinant protein control fragment (Product #RP-101099). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638625 |
Product Specific Information
Immunogen sequence:
LLHYLYTGEF GMEDSRFQNV DILVQLSEEF GTPNSLDVDM RGLFDYMCYY DVVLSFSSDS ELVEAFGGNQ NCLDEELKAH KAVISARSPF FRNLLQRRIR TGEE
Highest antigen sequence identity to orthologs:
- Mouse: 98%
- Rat: 99%
Target Information
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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