Thermo Fisher Scientific ARTS Polyclonal Antibody
ARTS 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. Affinity Chromatography로 정제, PBS/glycerol buffer에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–100 of human Septin 4 (NP_5363411) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.08 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855761 |
Product Specific Information
Immunogen sequence:
MIKRFLEDTT DDGELSKFVK DFSGNASCHP PEAKTWASRP QVPEPRPQAP DLYDDDLEFR PPSRPQSSDN QQYFCAPAPL SPSARPRSPW GKLDPYDSSE
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis. A novel mitochondrial septin-like protein, designated ARTS (Apoptosis Related Protein in TGF-beta Signaling Pathway), was identified and is encoded by the human septin H5/PNUTL2/CDCrel2b gene.
ARTS localizes to mitochondria and translocates to the nucleus during apoptosis. It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents such as TNF-α and Fas ligand.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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