Thermo Fisher Scientific IL-15 Monoclonal Antibody (34559), APC
인간 IL-15에 특이적인 Mouse IgG1 단클론 항체로 APC 형광 표지됨. Flow Cytometry에 적합하며 교차반응 없음. 651/660 nm에서 여기/방출. 단백질 A/G 정제, 4°C 암소 보관.
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Thermo Fisher Scientific IL-15 Monoclonal Antibody (Clone 34559), APC
Applications
- Flow Cytometry (Flow): 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 34559 |
| Immunogen | E. coli-derived recombinant human IL-15 (Asn49–Ser162) |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608838 |
Additional Formats
- FITC (MA5-23664)
- PE (MA5-23561)
- PerCP (MA5-23663)
- Request custom conjugation available
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human IL-2, recombinant mouse IL-15, or recombinant human IL-21 is observed.
Target Information
IL-15 (Interleukin 15) is a cytokine involved in T and NK cell activation and proliferation. It shares receptor components with IL-2 and can regulate immune responses by competing for receptor binding. IL-15 activates JAK kinases and STAT3/5/6 transcription factors, influencing apoptosis inhibition and lymphocyte differentiation. It plays a key role in immune regulation, autoimmune disease pathogenesis, and inflammatory disorders such as rheumatoid arthritis, psoriasis, and pulmonary inflammation. IL-15 neutralization has shown therapeutic potential in models of psoriasis and diabetes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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