Thermo Fisher Scientific Carboxypeptidase B2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Inhibition Assays (IA)

Changes made per CRPIM2012292.

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified Human TAFI.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

26 mg/mL

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2229799

Product Specific Information

PA1-43056 detects TAFI in human samples.

PA1-43056 has successfully been used in Western blot and ELISA applications.

PA1-43056 was derived from purified human TAFI.

Target Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.