Thermo Fisher Scientific ADAMTS8 Monoclonal Antibody (OTI2H5), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family.
Members share several distinct protein modules, including:

• Propeptide region
• Metalloproteinase domain
• Disintegrin-like domain
• Thrombospondin type 1 (TS) motif

Individual members differ in the number of C-terminal TS motifs and may have unique C-terminal domains.
The enzyme encoded by this gene contains two C-terminal TS motifs and disrupts angiogenesis in vivo.
Several disorders, notably lung neoplasms, have been mapped near this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.