Thermo Fisher Scientific ZNF198 Polyclonal Antibody
ZNF198 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 ZNF198의 975-1025번 잔기 영역을 면역원으로 사용하였으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A301710Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF198 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 975 and 1025 of Human zinc finger protein 198 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
ZNF198 is a ubiquitously expressed nuclear protein with largely unknown physiological roles. It contains 5 N-terminal zinc finger motifs for protein-protein interactions, a central proline-rich domain, a C-terminal nuclear localization signal (NLS), and an acidic domain.
Chromosomal translocation involving ZNF198 and FGFR1 produces a ZNF198/FGFR1 fusion kinase protein, which acts as a ligand-dependent, constitutively active tyrosine kinase. This fusion protein regulates STAT transcription factors (STAT1, STAT3, STAT5) and is associated with atypical myeloproliferative disease, peripheral blood eosinophilia, and T-cell leukemia/lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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