Thermo Fisher Scientific RASAL1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji
• Predicted reactivity: Mouse (85%), Rat (86%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene is a member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins, resulting in the inactive GDP-bound form of RAS and allowing control of cellular proliferation and differentiation. This family member is strongly and selectively expressed in endocrine tissues, and alternatively spliced transcript variants encoding different isoforms have been described.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.