Thermo Fisher Scientific MCP-2 Polyclonal Antibody, PeproTech

Thermo Fisher Scientific MCP-2 Polyclonal Antibody, PeproTech

Applications and Tested Dilution

Product Specifications

Product Specific Information

AA Sequence of Recombinant Protein:
QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP

Preparation:
Produced from sera of rabbits immunized with highly pure Recombinant Human MCP-2 (CCL8). Anti-Human MCP-2 (CCL8)-specific antibody was purified by affinity chromatography employing an immobilized Human MCP-2 (CCL8) matrix.

Sandwich ELISA:
To detect Human MCP-2 (CCL8) by sandwich ELISA (using 100 µL/well antibody solution), a concentration of 0.5–2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human MCP-2 (CCL8) (500-P35Bt) as a detection antibody, allows the detection of at least 0.2–0.4 ng/well of Recombinant Human MCP-2 (CCL8).

Western Blot:
To detect hMCP-2 by Western Blot analysis, this antibody can be used at a concentration of 0.1–0.2 µg/mL. Used in conjunction with compatible secondary reagents, the detection limit for Recombinant hMCP-2 is 1.5–3.0 ng/lane, under either reducing or non-reducing conditions.

Target Information

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.
This chemokine belongs to the CC subfamily, characterized by two adjacent cysteine residues. It shows chemotactic activity for monocytes, lymphocytes, basophils, and eosinophils. By recruiting leukocytes to sites of inflammation, this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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