Thermo Fisher Scientific CLCF1 Monoclonal Antibody (7E10)
CLCF1 단백질을 인식하는 마우스 IgM 모노클론 항체로 Western blot 및 ELISA에 적합합니다. 인간 반응성을 가지며 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- ELISA (ELISA): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7E10 |
| Immunogen | CLCF1 (AAH12939, 29 a.a. ~225 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NRTGDPGPGP SIQKTYDLTR YLEHQLRSLA GTYLNYLGPP FNEPDFNPPR LGAETLPRAT VDLEVWRSLN DKLRLTQNYE AYSHLLCYLR GLNRQAATAE LRRSLAHFCT SLQGLLGSIA GVMAALGYPL PQPLPGTEPT WTPGPAHSDF LQKMDDFWLL KELQTWLWRS AKDFNRLKKK MQPPAAAVTL HLGAHGF
Target Information
NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. It is expressed in lymph nodes and spleen, and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member b (LIFR-b) by binding and inducing tyrosine phosphorylation of these receptors.
In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B cell hyperplasia associated with increases in serum IgG and IgM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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