Thermo Fisher Scientific MMP7 Polyclonal Antibody
Rabbit polyclonal antibody against human MMP7 for WB and IHC applications. Detects 29.7 kDa protein. Supplied as liquid, 1 mg/mL concentration. Suitable for research use in extracellular matrix and tissue remodeling studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunohistochemistry (PFA fixed) (IHC-PFA) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the C-terminal of Human MMP7 (257–267 aa), conjugated to Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736158 |
Product Specific Information
A 1:1,000 dilution of PA5-77791 was sufficient for detection of MMP7 in 10 µg of rat kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects a 29.7 kDa protein.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of the extracellular matrix in physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in pathological processes including arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated upon cleavage by extracellular proteinases.
The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
It plays a role in wound healing and may regulate defensin activity in intestinal mucosa. The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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