Thermo Fisher Scientific FBXO8 Polyclonal Antibody
FBXO8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human과 Mouse에 반응하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA530512
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 114–319 of Human FBXO8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547986 |
Product Specific Information
- Recommended positive controls: Raji, JC
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (91%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid motif, the F-box. F-box proteins are subunits of the ubiquitin protein ligase complex SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
They are divided into three classes:
- Fbws containing WD-40 domains
- Fbls containing leucine-rich repeats
- Fbxs containing either different protein-protein interaction modules or no recognizable motifs
The protein encoded by this gene belongs to the Fbxs class and contains a C-terminal sequence similar to yeast Sec7p, a regulator of vesicular protein transport. It may interact with ADP-ribosylation factors (ARFs) and exhibit ARF-GEF activity.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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