Thermo Fisher Scientific FBXO6 Polyclonal Antibody
FBXO6 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태. 인간에 반응하며, 돼지·침팬지·소에서 예측 반응성 있음. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 48–293 of Human FBXO6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547987 |
Product Specific Information
- Recommended positive control: 293T
- Predicted reactivity: Pig (82%), Chimpanzee (100%), Bovine (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. F-box proteins are part of the SCF (SKP1–Cullin–F-box) ubiquitin ligase complex, which mediates phosphorylation-dependent ubiquitination.
F-box proteins are classified into three groups:
- Fbws (containing WD-40 domains)
- Fbls (containing leucine-rich repeats)
- Fbxs (containing other protein-protein interaction modules or no recognizable motifs)
The FBXO6 protein belongs to the Fbxs class and its C-terminal region is highly similar to rat NFB42, which may be involved in cell cycle control.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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