Thermo Fisher Scientific KCNMA1 Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
OSP00105W-100UL | - | Thermo Fisher Scientific OSP00105W-100UL KCNMA1 Polyclonal Antibody 100 ul pk | 재고문의 | pk | 565,000원 | - | 621,500원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:2,000
Immunohistochemistry (IHC)
1:2,000
Miscellaneous PubMed (Misc)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Mouse, Non-human primate, Rat
Published species
Not Applicable
Host/Isotype
Rabbit / Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from rat KCNMA1 conjugated to blue carrier protein was used as the antigen
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse.
Specificity of this antibody: KCNMA1.
Target Information
Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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