Thermo Fisher Scientific KCNMA1 Polyclonal Antibody
KCNMA1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC에 사용 가능. Rat 유래 합성 펩타이드 항원으로 제작되었으며, Mouse, Rat, Non-human primate 반응성. 연구용으로 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
- Publications: 참고 문헌 보기
Immunohistochemistry (IHC)
- Tested Dilution: 1:2,000
- Publications: 참고 문헌 보기
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat KCNMA1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse.
- Specificity: KCNMA1.
Target Information
Potassium channels are ubiquitously expressed proteins with diverse functions in excitable and non-excitable cells.
The large conductance, calcium-activated potassium channel (Maxi K+) differs from other potassium channels as its activation is controlled by both intracellular calcium increase and membrane depolarization.
The Maxi K+ channel core is an alpha homotetramer containing a voltage sensor and an intracellular calcium binding domain.
In vascular smooth muscle, an auxiliary beta-subunit exists in 1:1 stoichiometry, reducing by 5–10 fold the calcium concentration required to keep the pore open.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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