
Thermo Fisher Scientific Felvizumab Humanized Recombinant Human Monoclonal Antibody
RSV를 표적으로 하는 인간화 재조합 단일클론 항체로, ELISA 등 연구용에 적합. CHO 세포에서 발현되었으며, Protein A 정제 방식 사용. 낮은 엔도톡신 수준과 안정적인 액상 형태로 제공. 연구 전용 제품으로 진단용 사용 불가.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Respiratory syncytial virus (RSV) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.54 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910866 |
Product Specific Information
- Endotoxin level: < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Storage:
- 2–8°C for one week
- -20 to -80°C for twelve months from the date of receipt
Target Information
Felvizumab is a biosimilar antibody that targets respiratory syncytial virus (RSV). RSV belongs to the Paramyxoviridae family, subfamily Pneumovirinae, and causes common respiratory tract infections. Its genome is a single-stranded, negative-sense RNA encoding three envelope glycoproteins:
- SH protein (unknown function)
- G protein (attachment protein)
- F protein (fusion protein)
The F protein induces cell membrane fusion, forming syncytia. While RSV typically causes mild symptoms in adults, it is a major cause of lower respiratory tract infections and hospitalizations in infants and young children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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