Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Monoclonal Antibody (N10/2)
B세포 마커인 Lambda Light Chain을 인식하는 Monoclonal Antibody. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 인간 반응성, Mouse IgG1 kappa 형식, Protein A/G 정제, PBS buffer에 보존. 연구용 전용 제품.
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Thermo Fisher Scientific Lambda Light Chain (B-Cell Marker) Monoclonal Antibody (N10/2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N10/2 |
| Immunogen | Purified IgG from human serum |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure consisting of two heavy chains (five types) and two light chains (kappa and lambda, both with a molecular weight of approximately 22.5 kDa).
Kappa and lambda chains contain a variable and a constant region, easily differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is typically 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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