Thermo Fisher Scientific GUSB Recombinant Rabbit Monoclonal Antibody (4U0E2)
Human GUSB 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot 및 ELISA에 사용 가능. HEK293 세포에서 발현되며, 1.5 mg/mL 농도의 액상 형태로 제공. Lysosome 내 GUSB 검출에 적합하며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4U0E2 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human beta glucuronidase (GUSB) (NP_0001722) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911833 |
Product Specific Information
- Positive test controls: HepG2, A-549, HL-60
- Target localization: Lysosome
- Immunogen sequence:
MARGSAVAWA ALGPLLWGCA LGLQGGMLYP QESPSRECKE LDGLWSFRAD FSDNRRRGFE EQWYRRPLWE SGPTVDMPVP SSFNDISQDW RLRHFVGWVW
Target Information
The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans.
It is a tetrameric glycoprotein composed of identical subunits.
Mutations in the GUSB gene cause mucopolysaccharidosis type VII (MPS7; MIM 253220).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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