
Thermo Fisher Scientific LPP Recombinant Rabbit Monoclonal Antibody (8M2R8)
LPP 단백질을 인식하는 재조합 토끼 모노클로날 항체로, WB, IHC, ICC/IF, ELISA에 최적화되어 있습니다. 인간, 마우스, 랫트 반응성 확인. 고순도 친화 크로마토그래피 정제 및 안정적인 액상 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8M2R8 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human LPP (UniProt ID: Q93052) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911828 |
Product Specific Information
Positive test controls include HeLa, HepG2, NIH/3T3, and mouse lung.
The target protein is localized in cell junctions, cell membrane, cytoplasm, and nucleus.
Immunogen sequence:
MSHPSWLPPK STGEPLGHVP ARMETTHSFG NPSISVSTQQ PPKKFAPVVA PKPKYNPYKQ PGGEGDFLPP PPPPLDDSSA LPSISGNFPP PPPLDEEAFK
Target Information
This gene encodes a member of a subfamily of LIM domain proteins characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and motility. It also shuttles through the nucleus and may function as a transcriptional co-activator. The gene is located at the junction of certain disease-related chromosomal translocations that result in chimeric proteins promoting tumor growth. Alternate splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-42687_LPP_Q93052-1_Rabbit.svg, MA5-42687_LPP_Q93052-1_Rabbit_PDP.jpeg)
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