Thermo Fisher Scientific B7-H3 Recombinant Rabbit Monoclonal Antibody (317)
Thermo Fisher의 B7-H3 Recombinant Rabbit Monoclonal Antibody (Clone 317)은 마우스 B7-H3/CD276 단백질을 인식하는 고특이성 항체입니다. ELISA에 최적화되어 있으며, HEK293 세포에서 발현된 재조합 항체입니다. Protein A로 정제되어 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- ELISA (ELISA): 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 317 |
| Immunogen | Recombinant Mouse B7-H3/CD276 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912210 |
Product Specific Information
- Specificity: Mouse B7-H3/CD276
Target Information
CD276 (B7-H3) is a member of the B7 family of co-stimulatory molecules. It is a type I transmembrane protein that promotes proliferation of CD4+ and CD8+ T cells, enhances cytotoxic T cell generation, and selectively stimulates interferon gamma production.
Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines and is also found in various peripheral tissues such as heart, kidney, testis, and colon.
In humans, CD276 exists in two isoforms resulting from gene duplication and alternative splicing. It has potential therapeutic relevance in regulating cell-mediated immune responses to cancer, especially in combination with anti-angiogenic therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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