Thermo Fisher Scientific CCR1 Recombinant Rabbit Monoclonal Antibody (003)
Human CCR1 단백질을 인식하는 재조합 토끼 단클론 항체입니다. IHC(P) 실험에 최적화되어 있으며, 높은 특이성과 재현성을 제공합니다. Protein A로 정제된 액상 형태로, PBS 버퍼에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific CCR1 Recombinant Rabbit Monoclonal Antibody (Clone 003)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:250–1:1,000
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 003 |
| Immunogen | A synthetic peptide corresponding to the center region of the Human CCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912207 |
Product Specific Information
- Specificity: Human CCR1
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein-coupled receptors. The chemokine receptor subtypes can be divided into two major groups, CXCR and CCR, based on the two major classes of chemokines.
CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils, and binds macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines. Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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