Thermo Fisher Scientific Plakophilin-1 (PKP1) Monoclonal Antibody (10B2)
Plakophilin-1 단백질을 인식하는 Mouse monoclonal 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. Human 및 Mouse 시료에 반응하며, Protein A/G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10B2 |
| Immunogen | N-terminus of human Plakophilin-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Jul 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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