Thermo Fisher Scientific HK2 Monoclonal Antibody (OTI4D4), TrueMAB

Applications

Tested Application

• Western Blot (WB): 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

In vertebrates, there are four major glucose-phosphorylating isoenzymes: hexokinase I, II, III, and IV.
Hexokinase catalyzes the phosphorylation of glucose to produce glucose-6-phosphate, the first step in glycolysis.
Hexokinase 2 (HK2) is the predominant isozyme in insulin-responsive tissues such as skeletal muscle.
Its expression is insulin-regulated and has been linked to the elevated glycolytic rates observed in rapidly growing cancer cells.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.