Thermo Fisher Scientific HK2 Monoclonal Antibody (OTI4D4), TrueMAB
HK2 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. 인간 시료에 반응하며, 동결건조 형태로 제공. PBS 완충액에 8% 트레할로스 포함, 보존제 없음. 재구성 후 약 1 mg/mL 농도로 사용 가능.
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- CF500884
- 판매단위
- pk
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Applications
Tested Application
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D4 |
| Immunogen | Full length human recombinant protein of human HK2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
In vertebrates, there are four major glucose-phosphorylating isoenzymes: hexokinase I, II, III, and IV.
Hexokinase catalyzes the phosphorylation of glucose to produce glucose-6-phosphate, the first step in glycolysis.
Hexokinase 2 (HK2) is the predominant isozyme in insulin-responsive tissues such as skeletal muscle.
Its expression is insulin-regulated and has been linked to the elevated glycolytic rates observed in rapidly growing cancer cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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