
Thermo Fisher Scientific Human AMPK A2/B1/G1, GST Tag, His Tag Recombinant Protein
인간 유래 AMPK A2/B1/G1 재조합 단백질로 GST 및 His 태그 포함. 인산화 효소 활성 분석(Kinase Assay)에 적합하며, 고순도 정제 상태로 제공. 세포 에너지 대사 연구 및 당뇨병 관련 연구에 활용 가능. -80°C 보관, 동결·해동 반복 방지.
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Applications
- Kinase Assay (KA)
Tested Dilution: Assay-dependent
Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | Full length |
| Tag | GST-tag, His-tag |
| Molecular Weight | 91.4 / 57.8 / 41.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 0.02% Triton X-100, 50% glycerol, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
- For larger sizes, aliquoting may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
Protein Form: Full Length
Target Information
AMP-activated protein kinase (AMPK) is a heterotrimeric complex acting as a sensor of cellular energy levels. Activation of AMPK regulates metabolic pathways in liver, skeletal muscle, heart, adipose tissue, and pancreas. Dysregulation of AMPK signaling is linked to obesity and type 2 diabetes, where insulin resistance is prominent in skeletal muscle. Activation of AMPK is of interest for therapeutic research in type 2 diabetes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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