Thermo Fisher Scientific Calbindin/Calretinin Recombinant Rabbit Monoclonal Antibody (HL1787)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

HL1787

Immunogen

Recombinant fragment of human Calbindin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3094403

Target Information

Calbindin/Calretinin is a gene target that codes for two calcium-binding proteins that are expressed in different regions of the nervous system. Calbindin is mainly found in the cerebellum, while calretinin is expressed in the hippocampus, cortex, and other brain regions. These proteins play an essential role in calcium signaling, which is crucial for neuronal function and synaptic plasticity. They are also involved in other cellular processes, such as cell survival, differentiation, and gene expression. Dysregulation of calbindin/calretinin expression has been linked to various neurological disorders, including epilepsy, Alzheimers disease, and Parkinsons disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.