Thermo Fisher Scientific HDAC3 Recombinant Rabbit Monoclonal Antibody (HL1749)
HDAC3 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot 및 IHC(P) 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫드, 초파리에 반응. Protein A로 정제된 고순도 액상 항체로 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1749 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HDAC3. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094276 |
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.
This gene is regarded as a potential tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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