Thermo Fisher Scientific Paxillin Monoclonal Antibody (PXC-10)
Paxillin 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 ICC/IF에 적합. 다양한 종(인간, 생쥐, 닭 등)에 반응. 액상 형태, 6 mg/mL 농도, 4°C 보관 권장. 세포 부착 및 신호전달 연구에 활용 가능.
- 카탈로그번호
- MA124952
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:250 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chicken, Hamster, Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PXC-10 |
| Immunogen | Recombinant fragment (residues 305–559) of chicken Paxillin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6 mg/mL |
| Storage Buffer | Ascites |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_795141 |
Product Specific Information
MA1-24952 detects Paxillin from human, rat, bovine, chicken, and hamster samples.
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain, and this interaction is independent of the extracellular matrix. Although initially discovered in fibroblasts, paxillin phosphorylation may also play a role during neurite extension and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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