Thermo Fisher Scientific C1orf57 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
LALPVLRNAD CSSGPGQRVC VIDEIGKMEL FSQLFIQAVR QTLSTPGTII LGTIPVPKGK PLALVEEIRN RKDVKVFNVT KENRNHLLPD IVTCVQSSRK

Positive Samples: U-251MG, A-431, 293T

Target Information

C1orf57 (also known as nucleoside triphosphate phosphohydrolase) belongs to the THEP1 NTPase family. It and its mouse homolog (2310079N02Rik) are 190-amino-acid proteins with nucleotide phosphatase activity toward ATP, GTP, TTP, CTP, and UTP. Acting as a monomer, it hydrolyzes nucleoside diphosphates with lower efficiency.
The gene encoding C1orf57 is located on human chromosome 1, which spans about 260 million base pairs and represents approximately 8% of the human genome. This chromosome contains around 3,000 genes, many of which are associated with various diseases including Hutchinson-Gilford progeria (LMNA gene), familial adenomatous polyposis (MUTYH gene), Stickler syndrome, Parkinson’s disease, Gaucher disease, and Usher syndrome.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.