Thermo Fisher Scientific CDKL2 Polyclonal Antibody
Human CDKL2 단백질을 인식하는 Rabbit Polyclonal Antibody. Immunocytochemistry(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS(40% glycerol) 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDKL2. Recombinant protein control fragment (Product # RP-89787) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790660 |
Product Specific Information
Immunogen sequence:
NLIPRHQELF NKNPVFAGVR LPEIKEREPL ERRYPKLSEV VIDLAKKCLH IDPDKRPFCA ELLHHDFFQM DGFAERFSQE LQLKVQKDAR NVSLSKKSQN RKKEKEKDDS LVEERKTLVV QDTNADPK
Target Information
The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK1 and ERK2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group and closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain, and lung. It contains the conserved MAP kinase dual phosphorylation motif (Thr-Asp-Tyr) and is activated by EGF treatment. Unlike other MAP kinases, EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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