Thermo Fisher Scientific KLHL22 Polyclonal Antibody
Rabbit polyclonal antibody targeting human KLHL22 protein. Validated for ICC/IF applications with dilution range 0.25–2 µg/mL. Supplied as liquid unconjugated form at 0.1 mg/mL concentration. Suitable for research use only; store at 4°C short term or -...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KLHL22 (UniProt ID: Q53GT1-1, antigen range: 371–441, antigen length: 634) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790668 |
Product Specific Information
Immunogen sequence:
RYDPRHNRWF QIQSLQQEHA DLSVCVVGRY IYAVAGRDYH NDLNAVERYD PATNSWAYVA PLKREVYAHA G
Target Information
KLHL22 (kelch-like protein 22) is a 634 amino acid protein related to the Drosophila kelch protein, which is essential for maintaining Actin organization in ovarian ring canals. Mutations affecting Kelch function lead to failure of association with ring canals and female sterility.
Human KLHL22 contains six kelch repeats and one BTB (POZ) domain. The BTB domain is an N-terminal homodimerization domain involved in transcriptional regulation through chromatin structure control. Two isoforms of KLHL22 are produced via alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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