Thermo Fisher Scientific mTOR Monoclonal Antibody (GT649)
Thermo Fisher Scientific의 mTOR Monoclonal Antibody (GT649)는 인간 및 생쥐에 반응하는 단클론 항체로, 세포 성장과 증식 관련 mTOR 경로 연구에 적합합니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, 단백질 G 정제 및 액상 형태로 제공됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| in situ PLA (PLA) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT649 |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human mTOR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787136 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (90%), Sheep (98%).
- Positive Control: Jurkat, Raji, NCI-H929, 293T, A431, HeLa, HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-31505_mTOR_P42345-1_House_mouse.svg, MA5-31505_mTOR_P42345-1_House_mouse_PDP.jpeg)
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