Thermo Fisher Scientific MCF2 Polyclonal Antibody
MCF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 사용 가능하며 인간과 마우스 반응성. 액상 형태로 제공되며 -20°C 보관, GEF 활성 조절 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 872–1001 of human MCF2 (NP_0011653471) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805138 |
Product Specific Information
- Immunogen sequence:
VKMTWLKEIR NILLKQQELL TVKKRKQQDQ LTERDKFQIS LQQNDEKQQG AFISTEETEL EHTSTVVEVC EAIASVQAEA NTVWTEASQS AEISEEPAEW SSNYFYPTYD ENEEENRPLM RPVSEMALLY - Positive Samples: HT-29
- Cellular Location: Cytoplasm, Membrane
Target Information
Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes conversion of Rho family GTPases from GDP-bound to GTP-bound form.
- Isoform 1: No activity toward RHOA, RAC1, CDC42
- Isoform 2: Decreased GEF activity toward CDC42
- Isoform 3: Weak but significant activity toward RAC1 and CDC42
- Isoform 4: Significant activity toward RHOA and CDC42
- Truncated DBL oncogene: Active toward RHOA, RAC1, CDC42
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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