Thermo Fisher Scientific CD23 Recombinant Rabbit Monoclonal Antibody (PD00-03)
Recombinant rabbit monoclonal antibody targeting human CD23. Validated for IHC (paraffin) with high specificity. Suitable for detecting CD23 expression in human B cells and related tissues. Supplied as liquid, 1 mg/mL, purified via Protein A. For resea...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-03 |
| Immunogen | Recombinant protein within human CD23 aa 48–321 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093000 |
Product Specific Information
- Positive control: Human tonsil tissue, human lymph nodes tissue, human spleen tissue
- Predicted band size: 36 kDa
- Subcellular Location: Cell membrane, Secreted
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor found on B cells. CD23 expression has been observed in neoplastic cells from B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphomas. Functionally, CD23 is involved in B cell growth, differentiation, and IgE production. A soluble form of CD23 acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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