Thermo Fisher Scientific VISTA Monoclonal Antibody (B7H5DS8), PE, eBioscience
인간 VISTA 단백질을 인식하는 B7H5DS8 클론의 단일클론 항체로, PE 형광체가 결합되어 있습니다. Flow Cytometry용으로 최적화되어 있으며 생세포에서만 작동합니다. 488–561 nm 레이저에 적합하며 암 면역 연구에 활용됩니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific VISTA Monoclonal Antibody (B7H5DS8), PE, eBioscience
Thermo Fisher Scientific VISTA Monoclonal Antibody (B7H5DS8), PE, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 5 µL (0.125 µg)/test
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B7H5DS8 |
| Immunogen | VISTA-Fc protein |
| Conjugate | PE |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744697 |
Available Formats
Product Specific Information
Description:
This B7H5DS8 monoclonal antibody recognizes human VISTA, also known as B7-H5 or PD-1H. This clone has been tested and shown not to cross-react with human B7-H4, B7-H6, and B7-H7. This antibody works in flow cytometry only on live, not paraformaldehyde-fixed cells.
Applications Reported:
Reported for use in flow cytometric analysis.
Applications Tested:
Pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. Use at 5 µL (0.125 µg) per test. A test is defined as the amount of antibody that stains a cell sample in a final volume of 100 µL. Cell number may range from 10⁵ to 10⁸ cells/test.
Excitation/Emission:
488–561 nm / 578 nm
Laser Compatibility: Blue Laser, Green Laser, Yellow-Green Laser
Target Information
VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is encoded by the VSIR gene. Despite sequence homology with PD-L1, VISTA has a distinct expression pattern. In both mouse and human, it is predominantly expressed on hematopoietic cells—highest on myeloid cells, lower on T cells, and usually absent on B cells. VISTA on antigen-presenting cells suppresses CD4 and CD8 T-cell proliferation and cytokine production, making it a target for cancer immunotherapy. Known ligands include CD28H, VSIG-3, and VSIG-8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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