Thermo Fisher Scientific CRMP5 Polyclonal Antibody
CRMP5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제된 고순도 액상 항체. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 62–367 of Human CRMP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546951 |
Product Specific Information
- Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain
- Predicted reactivity: Mouse (97%), Rat (96%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The collapsin response mediator protein (CRMP) family (also referred to as ULIP6) plays key roles in growth cone guidance during neural development.
CRMP5 has relatively low sequence homology with other CRMP family members and is expressed in the developing nervous system, peaking during the first postnatal week.
Elevated levels of autoantibody to CRMP5 are linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms.
Autoimmunity against CRMP5, especially N-terminal epitopes, is being investigated as an oncological marker in the respiratory system and thymus.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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