Thermo Fisher Scientific ASB2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested dilution: 1:500–1:3,000
• View 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive control: HL-60
• Predicted reactivity: Mouse (93%), Rat (93%), Bovine (93%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The protein encoded by this gene belongs to the ankyrin repeat and SOCS box-containing (ASB) family. These proteins contain ankyrin repeat sequences and a SOCS box domain. The SOCS box couples suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, expression of this protein induces growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.