Thermo Fisher Scientific ASB2 Polyclonal Antibody
ASB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P) 실험에 적합합니다. Human 및 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:3,000
- View 2 publications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 210–453 of Human ASB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546952 |
Product Specific Information
- Recommended positive control: HL-60
- Predicted reactivity: Mouse (93%), Rat (93%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the ankyrin repeat and SOCS box-containing (ASB) family. These proteins contain ankyrin repeat sequences and a SOCS box domain. The SOCS box couples suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, expression of this protein induces growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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