
Thermo Fisher Scientific C12orf32 Monoclonal Antibody (OTI2C12), TrueMAB
인간 C12ORF32 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot에 적합하며, 고순도 친화 크로마토그래피 정제 제품. 동결건조 형태로 보존성이 우수하며, 연구용 DNA 손상 반응 관련 단백질 분석에 활용 가능.
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Thermo Fisher Scientific C12orf32 Monoclonal Antibody (OTI2C12), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Full length human recombinant protein of human C12ORF32 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RHNO1 plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation during the S phase.
It is recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in an ATR-dependent manner.
Required for the progression of the G1 to S phase transition and contributes to CHEK1 phosphorylation stimulation.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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