Thermo Fisher Scientific MDC1 Polyclonal Antibody
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Rabbit polyclonal antibody against human MDC1, validated for WB and IP applications. Recognizes region 475–525 of MDC1, with high specificity and cross-reactivity to primates. Supplied as liquid, unconjugated form, 1 mg/mL concentration, stored at 4°C ...
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 475–525 of human Mediator of DNA Damage Checkpoint 1 (MDC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Monkey and Chimpanzee
Target Information
MDC1 participates in the early response to DNA damage and is a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. It contains:
- N-terminus forkhead-associated (FHA) motif
- Two C-terminus BRCT motifs
- 13 internal repetitions of a 41 amino acid sequence
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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