Thermo Fisher Scientific Phospho-MAP2 (Thr1616) Polyclonal Antibody
MAP2 단백질의 Thr1616 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. 인간, 마우스, 비인간 영장류, 랫트 반응성. Western blot에 최적(1:1,000~1:3,000). 신경세포 구조 및 신경퇴행성 질환 연구에 적합.
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Thermo Fisher Scientific Phospho-MAP2 (Thr1616) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAP2 (Accession P11137), corresponding to amino acid residues around phosphorylated Thr1616 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903199 |
Product Specific Information
This antibody detects endogenous levels of MAP2 only when phosphorylated at Thr1616.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. Its expression is developmentally regulated, arising by alternative splicing of a single gene. MAP2 participates in microtubule assembly, an essential process in neurogenesis. In rat and mouse, MAP2 is a neuron-specific cytoskeletal protein enriched in dendrites, contributing to dendritic shape stabilization during neuron development. MAP2 is useful for studying neuronal structure in normal and malignant brain tissue, as well as in neurodegenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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