Thermo Fisher Scientific FOXC1 Polyclonal Antibody
FOXC1 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간 시료에 반응하며 WB에 사용 가능. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 민감도를 제공. 연구용으로만 사용 가능하며 -20°C에서 보관.
- 카탈로그번호
- PA518458
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 2–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DAVKDKEEKDRLH) corresponding to the internal amino acids of FOXC1 (aa 178–191) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981445 |
Product Specific Information
- Predicted to react with mouse and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
FOXC1 is a protein belonging to the forkhead family of transcription factors, characterized by a distinct DNA-binding forkhead domain. It plays a role in regulating the FGF19–FGFR4–MAPK pathway, promoting development and maintenance of anterior segment structures within the eye.
Mutations in FOXC1 cause various ocular anomalies such as glaucoma, iridogoniodysgenesis, Peters anomaly, and Axenfeld-Rieger anomaly, which may involve corneal and iris structural defects, dental anomalies, and developmental abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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