Thermo Fisher Scientific RAB3GAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 500-780 of human RAB3GAP1 (NP_001165906.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB3GAP1,uniProtId:Q15042-1,ncbiNodeId:9606,antigenRange:500-780,antigenLength:981,antigenImageFileName:PA5-120651_RAB3GAP1_Q15042-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120651_RAB3GAP1_Q15042-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914223

Product Specific Information

Positive test controls include: HeLa, HepG2, Jurkat, Mouse lung, Mouse brain, Rat brain.

Immunogen sequence: GLASGPPDLR CCLLHQKLQM LNCCIERKKA RDEGKKTSAS DVTNIYPGDA GKAGDQLVPD NLKETDKEKG EVGKSWDSWS DSEEEFFECL SDTEELKGNG QESGKKGGPK EMANLRPEGR LYQHGKLTLL HNGEPLYIPV TQEPAPMTED LLEEQSEVLA KLGTSAEGAH LRARMQSACL LSDMESFKAA NPGCSLEDFV RWYSPRDYIE EEVIDEKGNV VLKGELSARM KIPSNMWVEA WETAKPIPAR RQRRLFDDTR EAEKVLHYLA IQKPADLARH L

Target Information

RAB3GAP1, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.