Thermo Fisher Scientific PRELP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human PRELP (NP_002716.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRELP,uniProtId:P51888-1,ncbiNodeId:9606,antigenRange:200-360,antigenLength:382,antigenImageFileName:PA5-120649_PRELP_P51888-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120649_PRELP_P51888-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.14 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914221

Product Specific Information

Positive test controls include: Mouse lung, Rat heart.

Immunogen sequence: LDLQHNRLSD GVFKPDTFHG LKNLMQLNLA HNILRKMPPR VPTAIHQLYL DSNKIETIPN GYFKSFPNLA FIRLNYNKLT DRGLPKNSFN ISNLLVLHLS HNRISSVPAI NNRLEHLYLN NNSIEKINGT QICPNDLVAF HDFSSDLENV PHLRYLRLDG N

Target Information

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.