Thermo Fisher Scientific Human RHBDD3 Synthetic Peptide
인간 RHBDD3 단백질의 중심부 13 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단용으로 사용 가능하며, PBS 완충액에 0.1% BSA와 0.02% sodium azide가 포함된 액상 형태. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0976
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the center of human RHBDD3.
PEP-0976 can be used as a blocking peptide with polyclonal antibody PA5-20862.
Target Information
The Rhomboid family of proteins is composed of conserved polytopic membrane serine proteases involved in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells increased apoptotic activity and caspase activation in response to bromocriptine, suggesting that reactivation of RHBDD3 in tumors may be therapeutically useful. Reduced RHBDD3 expression has also been observed in several primary colorectal tumors, indicating that its loss contributes to decreased apoptotic response and potential malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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