Thermo Fisher Scientific MC3R Polyclonal Antibody
Rabbit polyclonal antibody against human MC3R for IHC(P) applications. Recognizes C-terminal peptide of MC3 receptor. High specificity and cross-species reactivity. Suitable for research on energy homeostasis and obesity mechanisms.
- 카탈로그번호
- PA533924
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–12 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-Terminus of human MC3 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551292 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human (100%); Gorilla, Gibbon, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig (94%);
Bat, Rabbit, Platypus (89%); Opossum, Turkey, Chicken, Xenopus, Trout (83%). - Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
Target Information
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes.
It maps to the same region as the locus for benign neonatal epilepsy.
Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role in energy homeostasis.
Mutations in this gene are associated with susceptibility to obesity in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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