Thermo Fisher Scientific Mammaglobin B Polyclonal Antibody
Rabbit 폴리클로날 항체로, Mammaglobin B 단백질 검출용. Western blot 및 IHC(Paraffin) 적용 가능. 고순도 액상 형태(1 mg/mL)로 제공되며, -20°C 보관. 암 연구 및 유방암 조직 분석에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from human Mammaglobin B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554707 |
Target Information
Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of endocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein (estramustine-binding protein), the major secretory glycoprotein of the rat ventral prostate gland.
Lipophilin A (LIPA, LPHA, SCGB1D1) is a component of a heterodimeric molecule present in human tears.
Lipophilin B (LIPB, LPHB, SCGB1D2) mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin.
Histological detection in breast tissue of Mammaglobin A (MGB1, SCGB2A2) and Mammaglobin B (MGB2, LPHC, UGB3, SCGB2A2) is a reliable diagnostic marker for breast tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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