Thermo Fisher Scientific LL-37 Polyclonal Antibody
LL-37 항균 펩타이드에 특이적인 Thermo Fisher Scientific의 Sheep Polyclonal 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인체 시료 반응성, 동결건조 형태로 제공되며 연구용으로 적합.
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Thermo Fisher Scientific LL-37 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Cathelicidin antimicrobial peptide conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in skin.
Besides direct antimicrobial function, Cathelicidins play multiple roles in innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment.
Cathelicidin antimicrobial peptides are prototypes of innovative drugs that may be used to treat infection and/or modulate immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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