Thermo Fisher Scientific scrambled Cathelicidin Polyclonal Antibody
인간 Cathelicidin의 스크램블드 펩타이드 항원을 인식하는 Rabbit Polyclonal 항체입니다. 항균 펩타이드 연구용으로 적합하며, 동결건조 형태로 제공됩니다. 4°C 단기 보관, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic scrambled peptide form of human Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: scrambled form of Cathelicidin antimicrobial peptide (the antigen).
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in the skin.
Beyond their direct antimicrobial function, Cathelicidins play multiple roles in innate and adaptive immunity, including:
- Endotoxin neutralization
- Angiogenesis and wound healing promotion
- Neutrophil chemotaxis and mast cell recruitment
Cathelicidin antimicrobial peptides are potential prototypes for innovative drugs to treat infections or modulate immune responses.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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