Thermo Fisher Scientific TRPM7 Monoclonal Antibody (M573)
TRPM7 단백질을 인식하는 마우스 단클론 항체(M573)로, Western blot에 최적화되어 있습니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C 보관, 연구용 전용 제품입니다.
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- pk
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Applications
Tested Application
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M573 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942722 |
Immunogen
Clone M573 was generated from TRPM7 synthetic peptide (coupled to carrier) corresponding to amino acids in the extracellular region of human TRPM7. This site is well conserved in rat and mouse TRPM7 but has low homology to other TRPM family members.
Product Specific Information
This antibody detects a 220 kDa* protein on SDS-PAGE immunoblots of human MCF7 cells.
Target Information
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that functions as both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it can phosphorylate itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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