Thermo Fisher Scientific Phospho-Filamin B (Ser2481) Polyclonal Antibody, Biotin
Phospho-Filamin B (Ser2481)을 인식하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체. Western blot, ELISA, IP 등 다양한 응용에 적합. Human 및 Mouse 시료에 반응하며, 고순도의 Affinity chromatography 정제 항체.
- 카탈로그번호
- PFLNB-240BIOTIN
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 2450–2500 on human Phospho-Filamin-B. Phosphorylated at Ser2481 residue. |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) containing 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus, and is predominantly expressed in many malignant tissues such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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