Thermo Fisher Scientific TRPM7 Monoclonal Antibody (S74), PerCP
TRPM7 단백질을 검출하기 위한 PerCP 결합 단클론 항체로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 고순도 Protein G 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TRPM7 Monoclonal Antibody (S74), PerCP
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S74 |
| Immunogen | Fusion protein amino acids 1817–1863 (C-terminus) of mouse TrpM7 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931879 |
Additional Formats
Product Specific Information
1 µg/mL of MA5-45425 was sufficient for detection of TrpM7 in 10 µg of COS cell lysate transiently transfected with TrpM7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 220 kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
Target Information
TRPCs are mammalian homologs of the Drosophila transient receptor potential (trp) protein and function as ion channels mediating capacitative calcium entry into cells. TRP-PLIK acts both as an ion channel and a kinase, conducting calcium and monovalent cations to depolarize cells and increase intracellular calcium. Its kinase activity is essential for channel function, depending on intracellular ATP and kinase mutants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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