Thermo Fisher Scientific Phospho-ZIPK (Thr265) Polyclonal Antibody
Phospho-ZIPK (Thr265) 폴리클로날 항체로 인간, 마우스, 랫트에 반응. WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 안정적인 저장용 PBS 버퍼 포함. DAPK3 인산화 부위 특이적 인식.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human DAPK3 around the phosphorylation site of T265 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610285 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
DAPK3 (Death-associated protein kinase 3) is a serine/threonine kinase involved in cell motility, smooth muscle contractility, and cell death processes. It is encoded by ZIPK and functions as a component of desmosomes and the epidermal cornified envelope in keratinocytes.
The N-terminal domain interacts with the plasma membrane, while the C-terminus associates with intermediate filaments. Through its rod domain, DAPK3 forms complexes with envoplakin, potentially linking the cornified envelope and desmosomes.
Additionally, DAPK3 interacts with AKT1/PKB, suggesting a role in AKT1-mediated signaling and cellular localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-40234_ZIPK_O43293-1_Rabbit.svg)
(이미지 파일명: PA5-40234_ZIPK_O43293-1_Rabbit_PDP.jpeg)
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